NCBI Databases & Resources

A guide to NCBI's databases, including NCBI Nucleotide and BLAST.

Where do I start?

There are hundreds of resources available for researchers to find information about genes, proteins, and everything in between. The National Center for Biotechnology Information (NCBI) offers a suite of tools that contain NCBI curated resources and pull from a variety of resources, including the European Bioinformatics Institute (EMBL-EBI) and the DNA Data Bank of Japan.

Which tool you use depends on what type of question you are trying to answer. 

What do you need to do? NCBI Tool
Find a DNA or RNA sequence Nucleotide

Find information about a specific known gene, including gene expression, splice variants, etc.

For example, "In what normal tissues is GENE XYZ express?"

For example, "Do we know if any microarray experiments have been done that have shown changes in this gene's expression?"

Gene

Find out which gene is related to a condition

For example, which gene(s) are related to lactose intolerance

PubMed + Gene

Identify and compare sequences

For example, which areas are similar between a mouse and a snake's genome?

 

BLAST
Find protein information and sequence information Protein
   

 

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